Manchester City seized the opportunity of Arsenal's 2-1 loss at Aston Villa earlier in the day to climb within two points of the leaders.
Defeat by arch-rivals Liverpool on Sunday has threatened to expose Manchester United's Premier League title challenge at the time in the season when they usually come to life.
Liverpool put their recent troubles behind them, showing touches of their best early-season vibrancy to overcame Arsenal 3-1 at a jubilant Anfield and leapfrog the Gunners into third place in the Premier League on Saturday.
Goalkeeper De Gea was forced to leave the field during Spain's Euro 2020 qualifier against Sweden on Tuesday.
England striker Wayne Rooney hit a quickfire double, his first league goals of the year, to power Manchester United to a 2-0 victory over Newcastle United.
Images from the English Premier League matches played on Saturday, April 13.
Anthony Martial introduced himself to Manchester United fans with a superb goal to complete a 3-1 win over bitter rivals Liverpool and cap a much-improved performance from Louis van Gaal's side on Saturday.
A ninth successive win in all competitions for United was celebrated with real vigour, as they moved to within a point of City in second, giving Arsenal the chance to go eight points clear at the top of the standings with a win over Tottenham Hotspur on Sunday.
Premier League heavyweights Liverpool and Manchester United were caught by late sucker punches in two games that finished far more dramatically than they began on Sunday.
'The run of titles that we won under Sir Alex, I don't think that's going to be easy for anyone to emulate or copy'
Images from Sunday's Premier League matches.
Images from Saturday's action in the Premier League.
A round-up of Saturday's action in the Premier League.
IMAGES from the English Premier League matches played on Saturday
IMAGES from the EPL matches played on Saturday.
Gakpo says Dutch skipper Van Dijk persuaded him to join Liverpool
A summary of Saturday's matches in the Premier League.
Manchester United forward Cristiano Ronaldo will not play against Liverpool
IMAGES from the English Premier League match played on Saturday
Leicester City must wait at least one more day for their first-ever Premier League title after drawing 1-1 with Manchester United at Old Trafford on Sunday.
Injured striker Robin van Persie is expected to miss Manchester United's Capital One Cup tie against Liverpool on Wednesday but could be fit for Saturday's Premier League clash with West Bromwich Albion.
Norwich sign Williams on loan from Manchester United.
Ivan Toney, once Brentford's lynchpin in attack, has moved to Al-Ahli for 40 million pounds ($52.50 million).
Liverpool rekindled the title race on Saturday with a 4-1 mauling of Premier League leaders Manchester United at Old Trafford.
Manchester City went 11 points clear with a record 14th consecutive Premier League win in an entertaining derby against Manchester United at Old Trafford.
IMAGES from the English Premier League matches played on Sunday.
ManchesterCity and Manchester United scored 10 goals between them and boosted their title aspirations with convincing wins over NorwichCity and Fulham respectively on an eventful afternoon in the Premier League on Saturday.
Manchester City came from behind twice to earn a 2-2 draw with Liverpool in a breathless and pulsating Premier League encounter, at Anfield, on Sunday. All four goals came in the second half.
Images from Sunday's action in the Premier League.
Jose Mourinho's first Premier League game as manager of Manchester United ended in a comfortable 3-1 victory away to Bournemouth on Sunday.
The last three league meetings between the two sides, including October's game at Anfield, have ended in draws but Lovren said Liverpool were intent on coming away with all three points on Saturday.
Liverpool climbed to the top of the Premier League table with a 2-1 victory over struggling Wolverhampton Wanderers on Saturday.
Defending champions Manchester City dominated the Professional Footballers' Association's (PFA) Team of the Year announced on Thursday, claiming six out of 11 spots.
Liverpool's English Premier League title winning captain Jordan Henderson was named England's Footballer of the Year on Friday in the annual vote of the Football Writers' Association (FWA).
Manchester United climbed back up to second in the table after second-half goals by Anthony Martial and Jesse Lingard earned a 2-0 victory at Everton -- their first win in five games in all competitions.
The fixture was originally scheduled to be played on May 3 but was postponed after violent clashes between fans and police in which more than 100 supporters forced their way into the stadium and stormed the pitch to protest against the club's owners -- the Glazer family.
Holders Manchester City beat Chelsea 1-0 with a late Bernardo Silva goal on Saturday to reach the FA Cup final after an absorbing end-to-end Wembley semi-final left the exhausted winners still chasing a domestic double.
IMAGES from the Premier League matches played on Saturday.
IMAGES from Premier League matches played on Saturday
